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Weight Loss Pills UK: Every Prescription Tablet Compared

Three weight loss pills are licensed in the UK: the Wegovy pill, Foundayo and orlistat. The Wegovy pill starts from

Total
£52.99
for a month today at the cheapest checked pharmacy. This guide covers how each pill works, who qualifies and which pills to avoid.

  • Independent: Ogovy does not sell medicines
  • Live prices, checked several times a day
  • Every pharmacy GPhC checked by hand
Quick answer

The Wegovy pill (oral semaglutide) and Foundayo (orforglipron) are the two daily GLP-1 tablets licensed for weight loss in the UK. The Wegovy pill starts from

Total
£52.99
for a first order today. Orlistat is the older option and works in a different way. All three need a prescription or a pharmacist’s check. Diet pills sold without one are not licensed.

Live Wegovy pill prices by dose

The lowest delivered price for one month at each dose, for a first order, across every pharmacy Ogovy checks. No pharmacy is named here, so none gets a free plug. The ranked list shows who charges what.

1.5mg
Total
£52.99
4mg
Total
£72.99
9mg
Total
£82.99
25mg
Total
£128.00

Last checked 9 Nov 2026. Prices move through the day. See the full Wegovy pill price list for every pharmacy, repeat-order prices and codes.

The four licensed GLP-1 weight loss medicines compared

Four GLP-1 style medicines are licensed for weight loss in the UK and sold through online pharmacies. Each has its own Medstack price site, with live prices for every dose.

MedicineHow to takeMain trial resultNHS statusLive prices
Mounjarotirzepatide, Eli LillyPen, once a week20.9% average weight loss on 15mg over 72 weeks (SURMOUNT-1)NICE TA1026, phased NHS roll-outMounjaro prices
Wegovy injectionsemaglutide, Novo NordiskPen, once a week14.9% average weight loss on 2.4mg over 68 weeks (STEP 1)NICE TA875, specialist weight servicesWegovy injection prices
Wegovy pilloral semaglutide, Novo NordiskTablet, once a day before foodAbout 14% average weight loss on 25mg over 64 weeks (OASIS 4)Not on the NHS yet, NICE review to followPrice list here
Foundayoorforglipron, Eli LillyTablet, once a day, no food rules11.2% average weight loss on the top trial dose over 72 weeks (ATTAIN-1)NICE appraisal ID6516 under wayFoundayo prices

Trial figures are averages from separate placebo-controlled trials with different people, lengths and doses. They do not rank one medicine above another. Your prescriber will advise on the right choice for you.

The three licensed weight loss pills

Wegovy pill

Oral semaglutide from Novo Nordisk, approved by the MHRA in June 2026. One tablet a day, taken on an empty stomach. Doses climb from 1.5mg to 4mg, 9mg and 25mg, with at least a month at each step.

What is the Wegovy pill?

Foundayo

Orforglipron from Eli Lilly, licensed in August 2026. One tablet a day with no food or water rules. Live prices sit on our sister site Dayo.

Foundayo vs Wegovy pill

Orlistat

An older tablet taken with each main meal. Orlistat stops your gut absorbing some of the fat you eat. Weight loss is smaller than with the GLP-1 tablets, and oily stools are common.

How to take the Wegovy pill

The Wegovy pill needs a strict morning routine, because food and drink stop the tablet being absorbed. The MHRA gives these steps:

  1. Fast for at least eight hours, usually overnight.
  2. Swallow the tablet whole with a sip of water.
  3. Wait at least 30 minutes before food, drink or other tablets.

Miss the routine and less medicine reaches your blood. If you want a tablet without the fasting rules, Foundayo has none.

Who qualifies for a weight loss pill

The MHRA licence for the Wegovy pill covers adults with a BMI of 30 or more, or a BMI of 27 to 30 with at least one weight-related condition such as high blood pressure or type 2 diabetes. The tablet sits alongside a reduced-calorie diet and more activity.

Online pharmacies apply these rules through a health questionnaire and a weight check. Some set a higher starting BMI of their own. The Wegovy pill is not yet on the NHS. NICE will decide on NHS use.

Pills to avoid

Search results and social media are full of “diet pills” sold without a prescription. None of them is licensed for weight loss in the UK. Some contain hidden medicines such as sibutramine, withdrawn years ago over heart risks.

  • No health questions before checkout: walk away.
  • No GPhC registration number on the site: walk away.
  • “Semaglutide drops” or “GLP-1 supplements”: not the licensed medicine.

Check any pharmacy on the General Pharmaceutical Council register. Every pharmacy on Ogovy has been checked by hand.

Pills or injections?

Tablets suit people who dislike needles or travel often. Weekly injections suit people who struggle with a daily routine. In trials, the injections produced larger average weight loss, and the Wegovy pill at 25mg came close to the Wegovy injection. Price depends on the dose you reach. See switching from Mounjaro to Wegovy pills if you are moving from an injection.

How Ogovy checks prices

Ogovy is run by Medstack Ltd, an independent UK company (Companies House 16439872). We do not sell, prescribe or dispense medicines. Prices are checked against each pharmacy’s own checkout several times a day and shown as the delivered total for one month. Every pharmacy’s certificates are checked by hand before listing. Some links earn a referral fee. Fees never change the order of the price table.

Weight loss pill questions

What weight loss pills are available in the UK?

Three licensed weight loss pills: the Wegovy pill (oral semaglutide), Foundayo (orforglipron) and orlistat. The first two are daily GLP-1 tablets. Orlistat is older and blocks some fat absorption.

How much is the Wegovy pill in the UK?

Ogovy shows the live delivered price for every Wegovy pill dose. The 1.5mg starting dose is the cheapest, and the price rises at 4mg, 9mg and 25mg.

Is the Wegovy pill available on the NHS?

Not yet. The Wegovy pill is available privately through UK online pharmacies. NICE will assess the tablet for NHS use.

Do weight loss pills work as well as injections?

In trials, the Wegovy pill at 25mg gave about 14% average weight loss over 64 weeks, close to the Wegovy injection. Mounjaro injections gave the largest average loss. Results vary between people.

Do I need a prescription for weight loss pills?

Yes for the Wegovy pill, Foundayo and prescription-strength orlistat. A lower-strength orlistat is sold by pharmacists after a check. Any other pill sold as a weight loss treatment without a check is not licensed.

Which weight loss pill has the fewest rules?

Foundayo. You take the tablet once a day at any time, with or without food. The Wegovy pill needs an eight-hour fast and a 30-minute wait after the dose.

Weight loss medicine guides across the Medstack sites

Each Medstack site covers one medicine in depth. These four guides compare the whole market from a different angle.

Health compare UK on every Medstack site: Monj · iGovy · Ogovy · Dayo.

More on Ogovy: Wegovy pill retail prices, Wegovy pill prices by pharmacy, Wegovy pill on the NHS.

Sources

  1. Medicines and Healthcare products Regulatory Agency. First GLP-1 tablet for weight loss approved in the UK, GOV.UK
  2. Wharton S et al. Oral semaglutide at a dose of 25 mg in adults with overweight or obesity (OASIS 4). New England Journal of Medicine, 2025
  3. Wharton S et al. Orforglipron, an oral small-molecule GLP-1 receptor agonist for obesity treatment (ATTAIN-1). New England Journal of Medicine, 2025
  4. Wilding JPH et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). New England Journal of Medicine, 2021
  5. General Pharmaceutical Council. Register of pharmacies
  6. Medicines and Healthcare products Regulatory Agency. Yellow Card reporting scheme